Investigation of the Stress-Induced Nuclear Localisation of Retinoblastoma Binding Protein 6 (Rbbp6) and its Role in Ubiquitination Of Y-Box Binding Protein-1 (Yb-1)
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Date
2017
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Publisher
University of the Western Cape
Abstract
Retinoblastoma Binding Protein 6 (RBBP6) is a 200 kDa RING finger-containing human
protein known to serve as an E3 ubiquitin ligase, and to play a role in ubiquitination and
suppression of the tumour suppressor p53. It also regulates the stability of mRNA
transcripts by modulating 3'-polyadenylation.
Description
Magister Scientiae - MSc (Biotechnology)