Browsing by Author "Salubi, Christiana Abimbola"
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Item Heterogeneous vanadium Schiff base complexes in catalytic oxidation reactions(Growing Science, 2023) Salubi, Christiana AbimbolaThe chemistry of Schiff base has received remarkable attention in different applications, both organic synthesis and industries. Over the past few years many reports have been on the synthesis, characterization and application of vanadium Schiff base complexes. However, heterogeneous vanadium Schiff base catalysts are active for various oxidation reactions, making catalytic oxidation of hydrocarbons a great interest. This review summarizes the recent development of organic substrate oxidation with heterogeneous vanadium Schiff base catalysts.Item Synthesis of new biguanide derivatives as potential antidiabetic drugs(University of the Western Cape, 2022) Salubi, Christiana Abimbola; Titinchi, SalamThe main purpose of this study was to synthesize biguanide compounds with potential as antidiabetic drugs. All biguanide compounds possess antidiabetic properties by decreasing the blood glucose level. Hence, we embarked on the synthesis of a series of biguanides in a threestep reaction which involves synthesis of a Schiff base, reduction of the Schiff base to a secondary amine using sodium borohydride and lastly formation of substituted biguanide derivatives with amines (primary or secondary) and dicyandiamide.