Research Articles

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Browsing by Author "Abdulrab, Saleem"

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    Antibacterial and anti‑inflammatory efficacy of n‑acetyl cysteine in endodontic treatment: A scoping review
    (BMC, 2022) Abdulrab, Saleem; Mostafa, Nawras; Al‑Maweri, Sadeq Ali
    This scoping review systematically summarized the available evidence about the efficacy of N-acetyl cysteine (NAC) as an intracanal antibacterial and/or anti-inflammatory.PubMed, Scopus, Web of Science, and Google scholar search engines/databases were searched up to February 2022 to retrieve relevant studies. The studies were evaluated for eligibility criteria, and identifying relevant studies.Out of 193 studies, 15 fulfilled the inclusion criteria and were processed for data extraction. Thirteen in vitro studies assessed antibacterial/antibiofilm efficacy of NAC, and reported good and promising efficacy: NAC was found as efficacious as the comparators (chlorhexidine, sodium hypochlorite, calcium hydroxide), or even showed higher efficacy.
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    The influence of horizontal glass fiber posts on fracture strength and fracture pattern of endodontically treated teeth: A systematic review and meta-analysis of in vitro studies
    (Wiley, 2022) Abdulrab, Saleem; Geerts, Greta; Al-Maweri, Sadeq Ali
    This systematic review and meta-analysis aimed to summarize available evi-dence regarding the effect of horizontal glass fiber posts (HGFPs) on fracture strengthand fracture pattern of endodontically treated teeth (ETT) compared to controls withoutHGFP. The review protocol was registered on the OSF registries.Literature searches were conducted in MEDLINE/PubMed, Scopus, Web ofScience, Embase, Google Scholar, and ProQuest for all relevant studies published upto February 2022. All in vitro studies that assessed the influence of HGFPs on fracturestrength and fracture pattern of ETT whether mesio-occluso-distal or mesio-occlusalor DO cavities were considered eligible. Review Manager (RevMan) was used forthe meta-analysis. Subgroup and funnel plot analyses were also performed. Qualityassessment was conducted by two independent reviewers.
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    Statins-based prophylactic mouthwash and nasal spray may protect against coronavirus disease 2019
    (Elsevier, 2020) Abdulrab, Saleem; Alkadasi, Baleegh A.; Al-Maweri, Sadeq
    The novel coronavirus 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused an unprecedented healthcare crisis. SARS-CoV-2 gets access into the human body mainly through the nose and the mouth and invades these mucosae in its destination to the pulmonary tissues. Thus, the oral and nasal mucosae serve as the main routes and reservoirs for aerosolized transmission of the viral particles to the external environment and hence infection transmission. Statins have been shown to have antimicrobial, antiviral, antifungal, anti-inflammatory, immunomodulatory, and antioxidant properties. Therefore, we hypothesize that using statins-based prophylactic mouthwashes will reduce COVID-19 transmission in dental settings.